ADM-201 dump PMP dumps pdf SSCP exam materials CBAP exam sample questions

阿尔茨海默病:为何不能治愈? – 译学馆
未登陆,请登陆后再发表信息
最新评论 (0)
播放视频

阿尔茨海默病:为何不能治愈?

Why is Alzheimer's still a medical mystery? | The Economist

我们所知道的阿尔茨海默病
what we know about Alzheimer’s
随着人口老龄化的严重
As populations have aged
痴呆症已经极速成为
…dementia has soared to become…
全球死因第五位
…the fifth leading cause of death worldwide
阿尔茨海默病是痴呆症的一种
Alzheimer’s disease, a form of dementia…
占了痴呆症的很大一部分
…accounts for most of these cases
在过去的几十年里数百亿美元被用于
Tens of billions of dollars have been spent on…
阿尔茨海默病的研究
Alzheimer’s research over the past several decades
但是仍然没有治愈的方法
but still there is no cure
所有阻止病情加重的治疗都失败了
All attempts to halt the progression of the disease have failed
现在许多大型制药公司已经退出了研究
Now many major drug companies have pulled out of research altogether
所以为何阿尔茨海默病仍是医学难题?
So why is Alzheimer’s disease still such a medical mystery?
阿尔茨海默病的症状之一是随着时间流逝
One of the signs of Alzheimer’s in the brain
大量神经元的链接被损伤
is damage of connections…
大量神经元死亡
…and the loss of large numbers of neurons over time
阿尔兹海默病影响了海马体
It affects the hippocampus…
及其连接结构
…and its connected structures…
使海马体更难形成新的记忆或者学习新的信息
…making it harder to form new memories or learn new information.
随着损伤在大脑中扩散
As damage spreads through the brain…
大脑皮层会变得更薄
…the cortex becomes thinner…
更多的记忆还是会消失
…and more memories are lost…
尽管情绪反应仍然存在
…although emotional responses can often remain…
当大脑进一步萎缩
As the brain shrinks further…
它慢慢改变一个人的性格和行为
…it slowly alters personality and behaviour…
最终改变其独立生活和行为的能力
…and eventually the ability to live and function independently
35年来 对于这种疾病的起源
For 35 years there has been scientific disagreement…
科学上一直存在分歧
…about the origins of the disease
主要的争议在于
The main area of debate has focused on…
一种异样聚集成块的蛋白
…the abnormal buildup of clumps of protein…
被称作淀粉样蛋白斑块
…called amyloid plaques…
常常出现在阿尔茨海默病患者的大脑中
…often found in brains of those affected by Alzheimer’s
但是所有尝试用来对付这种蛋白质的药物都失败了
But all attempts to target this protein with drugs have failed
一项新的研究正在改变
A new study is now challenging the way…
科学家对这种疾病的看法
…science thinks about the disease
这项研究表明牙龈中的
The study suggests that the bacterium Porphyromonas gingivalis…
牙龈卟啉单胞菌
…which is involved in gum disease…
可能导致阿尔茨海默病的发生
…may contribute to Alzheimer’s in…
在对老鼠的研究中
In studies on mice…
这种单胞菌可能引起大脑炎症
…the bacterium can cause brain inflammation…
神经损伤以及产生淀粉样蛋白斑块
…neural damage and amyloid plaques
研究人员接着在老鼠身上发现
The researchers went on to show in mice…
针对毒性酶的药物来停止神经损伤
…this damage could be stopped using drugs that target the toxic enzymes
不过 事实还远不止这些
There is more to this story though
阿尔兹海默病在
The risk of Alzheimer’s is higher…
那些头部严重受伤
…in those who have severe head injuries…
和患有动脉硬化的动脉疾病的人群中
…and also for those with an arterial disease…
发病率更高
…known as atherosclerosis
这说明很多的疾病都是殊途同归的
This suggests there are many causes with one end point
科学家们希望能找出它们相互之间
And scientists hope that finding an underlying cause…
联系在一起的根本原因
…that could tie these together…
这会是将来更好的治疗疾病的一个要素
…will hold the key to better treatments in the future
下一集 如何对抗疟疾
coming up next how to defeat malaria

发表评论

译制信息
视频概述

介绍了阿尔茨海默病的原因,以及目前科学家们对于该病的最新发现

听录译者

收集自网络

翻译译者

Qin Q

审核员

审核员XY

视频来源

https://www.youtube.com/watch?v=_kvIaHVUdLE

相关推荐