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为什么不喝咖啡我就头疼 – 译学馆
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为什么不喝咖啡我就头疼

Why Does Skipping Coffee Give Me Headaches?

你是否曾经没能喝上你的清晨咖啡
If you’ve ever missed your morning cup of joe
并被折磨死人的头痛打倒?
and been slammed with a killer headache?
你不是一个人
You are not alone.
戒除咖啡因的症状就是从头痛到疲乏
Withdrawal symptoms from caffeine, from headaches to fatigue,
这点在近两个世纪前就已经在医学上被证实了
have been reported in medical literature for nearly two centuries,
虽然同业互查研究是最近的
although most of the peer-reviewed research is more recent.
但事实就是咖啡因会使人上瘾
Fact of the matter is, caffeine is addictive
并影响你的大脑和神经系统
and affects your brain and nervous system.
医生表明它和其他会让人上瘾的药物比起来
Doctors consider it to be pretty benign compared
要好的多
to many other addictive substances.
但是你将变得越来越依赖于每天的咖啡
But you can become dependent on your daily coffee fix.
咖啡因通过干扰一种叫做腺苷酸的分子来产生效果
Caffeine works by interfering with a molecule called adenosine.
腺苷酸存在于你身体的各个角落
Adenosine is found all over your body.
但在你的大脑里 它的作用是协助调节不同的神经传导物质
But in your brain, it helps regulate different neurotransmitters
从而影响你对困意的感觉
and can influence how sleepy you feel.
每天 腺苷酸通过粘附在脑神经细胞末梢的受体上
By binding to receptors on your brain cells over the course of a day,
来提醒你的大脑该刹车休息了
adenosine basically tells your brain to step on the brakes.
因为咖啡因的分子结构和腺苷酸的分子结构见鬼般的相似
Because caffeine molecules look pretty darn similar to adenosine molecules,
它也能粘附在同样的受体上 阻滞腺苷酸的功能
caffeine can bind to the exact same receptors and block their function.
所以说 咖啡因抑制了腺苷酸执行它的职责
So caffeine stops adenosine from doing its thing,
然而那些兴奋的神经传导物质依然在周围
while some stimulating neurotransmitters are still around.
那就是为什么你觉得清醒警觉
That’s why you feel alert and awake.
现在 科学家们对咖啡因脱瘾背后的生物化学理论
Now, scientists aren’t entirely sure about the biochemistry
还无法完全确定
behind caffeine withdrawal.
一些研究认为如果你夜以继日地摄入咖啡因
Some studies suggest that if you have caffeine day in and day out,
你的脑细胞将会产生更多的腺苷酸受体
your brain cells start to make more adenosine receptors to compensate
来补偿给阻滞处 试着使你的大脑正常工作
for all the blockage, trying to keep your brain working normally.
所以如果你将晨间咖啡在你的方程式中删除掉
So if you take your morning coffee out of the equation,
腺苷酸突然有了多余的受体可供粘附
suddenly there are extra receptors available for adenosine to bind to,
改变了神经传递素的水平 你就会觉得疲惫
changing neurotransmitter levels and making you a little sleepier.
不论在分子层面上究竟发生什么
Regardless of what’s exactly happening on a molecular level,
不管你的大脑在什么时候变化……那是戒瘾的过程
when the chemistry of your brain changes… it’s a recipe for withdrawal.
在拒绝咖啡因后的12至24小时
Around 12 to 24 hours after quitting caffeine,
你的大脑的血流和脑电活动开始变化
your brain starts experiencing changes in blood flow and electrical activity.
这些改变可能导致头痛 疲劳
Those changes can lead to the headache, drowsiness,
或者是那些正摆脱晨间咖啡的人所说的警惕性下降
and decreased alertness reported by people who get rid of their morning coffee
这些症状会出现在任何地方并且持续两天至几周
which can last anywhere from two days to a couple weeks.
有时候 戒瘾也会被
Sometimes, withdrawal is also influenced
一种叫“期待理论”的心理现象所影响
by a psychological phenomenon called expectancy.
大致就是说如果你知道戒瘾会头痛这件事
Basically, if you’re aware that withdrawal headaches are a thing,
你也许就会认为这个会发生
you might expect them to happen
这种预感会影响你实际上感受到的症状
and that expectation could influence what symptoms you actually experience.
但是在2004年一份对超过50篇医学文献的综述中提到
But a 2004 review of over 50 papers from medical literature
至少有一些关于咖啡因脱瘾的研究
found that at least some studies of caffeine withdrawal
可以充分被用来证明“期待理论”并不影响他们带来的反应
were sufficiently designed to keep expectancy from affecting their results.
所以“期待理论”也许确实会对你的症状产生影响
So expectations might have some impact on your symptoms,
但是咖啡因脱瘾同样也会产生生理上的影响
but caffeine withdrawal definitely has a physiological impact too.
用另一句话来说 每天一杯双份焦糖玛奇朵
In other words, that daily double shot caramel macchiato
正完全改变着你的脑部化学过程
is totally altering your brain chemistry.
但是朋友 如果它能帮你集中精神
But, hey, if it helps you concentrate,
那或许也没多大害处
there doesn’t seem to be too much harm in it.
只要你不怕你停不下来
As long as you’re ok with never stopping!
谢谢提问 特别鸣谢所有在众筹网站上的赞助商
Thanks for asking, and special thanks to all of our patrons on Patreon!
如果你想看到更多关于咖啡因的Sci秀视频
If you want to see more SciShow videos about caffeine,
参考之前出现在屏幕上的链接
there’s a link to an early one in the description,
如果你只想和我们一起变得更聪明
and if you just want to keep getting smarter with us,
去youtube.com/scishow关注我们吧!
go to youtube.com/scishow and subscribe!

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视频概述

从科学角度来看为什么喜欢喝咖啡的人戒咖啡时会头痛并且觉得疲劳

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视频来源

https://www.youtube.com/watch?v=zGWZqpHcajY

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