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请让你的家人朋友多点了解:多发性硬化症(肌无力) – 译学馆
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请让你的家人朋友多点了解:多发性硬化症(肌无力)

What Is Multiple Sclerosis?

这个月 世界上的许多国家将会广泛的认识到
This month, many countries around the world will be spreading awareness on multiple
多发性硬化症(MS) 一种影响了世界上数百万人口的疾病
sclerosis, or ‘MS’. A disease that affects millions of people worldwide. But
什么叫做多发性硬化症呢? 首先 MS会影响
what exactly is multiple sclerosis? MS primarily affects the central
由大脑 脊髓 视神经组成的中枢神经系统
nervous system which consists of the brain, spinal cord and optic nerve. Just
这一系统功能是否正常决定了你日常所做的所有事
about everything you do depends on this system functioning properly, from
从呼吸到运动甚至看油管的视频 这些动作
breathing to moving and even watching youtube videos. And these actions are all
全都由你体内的神经细胞执行 这是一种在我们之前的视频里经常提到的细胞
facilitated by neurons throughout your body, cells which we’ve talked about many
这些神经细胞能以难以置信的速度传送信号
times in our previous videos. These neurons are able to send signals all
部分的原因是
throughout the body at incredible speeds, in part because of the fatty
包围在它们周围的外衣
coating that surrounds them
一种叫髓鞘或者髓磷脂的物质
something called myelin or the myelin sheath.
髓鞘将神经冲动隔绝起来 使神经冲动到达它们的终点
This myelin insulates the impulses and allows the nerve signals to reach their
这正是MS患者出问题的地方
destination, however in the case of MS this is where the issues occur.
免疫系统有抵御病毒 细菌 寄生虫 使人们免于疾病的功能
The immune system is designed to fight off disease from viruses, bacteria,
它们通过从健康组织中消化病毒等来执行功能
parasites or other agents and does so by distinguishing these things from healthy
但是在MS患者中 免疫系统不会攻击多余的髓磷脂
tissue. But in the case of MS, the immune system ends up attacking the myelin in
所以这被归类为自身免疫紊乱
what is classified as an auto-immune disorder.
这种过程将会导致疤痕组织的增生 这就是
This process of de-myelination can lead to a build above scar tissue, hence the
硬化二字的由来 接着 中枢神经系统就不能正常输送和接受信号
word sclerosis. The CNS then becomes unable to send and receive signals
神经冲动传输的速度将会降低 甚至停止
properly. Messages traveling along neurons may be slowed down, distorted or
因为神经走行 位置和髓鞘形成的原因
stopped altogether. Because of the bearing, locations and nature of de-myelination,
MS患者的症状也多种多样 包括
the symptoms of MS are incredibly diverse. They can range from
肌无力 肌肉不协调 疲劳 视力障碍 肌肉麻木
muscle weakness to decreased coordination, fatigue, vision problems, numbness or even
甚至肌肉麻痹
paralysis.
MS可以通过对大脑进行核磁共振扫描观察是否有损伤或瘢痕
Though an MRI scan of the brain to look for lesions or scarring is integral
来诊断
to diagnosis.
有一些患者的症状十分的明显而危急 而有的则更缓慢
For some, the symptoms come as acute episodes while others experience more
永久 随着时间恶化 对于这种疾病 我们还不知道发病的原因
chronic and permanent symptoms, which worsen over time. At this point no true
或者治疗方法 目前研究表明MS有可能跟环境因素 滤过性毒菌
cause or cure is known. While potential links to environmental factors, viral
和基因因素有关 目前研究仍在进行
infections and genetics have been found, studies are ongoing and not yet
仍然没有明确结论 尽管研究人员已经使用了多种方法试图缓解症状
conclusive. And while their has been a lot of work towards not only alleviating some of the
和病情 但这些方法对所有MS患者的效果
symptoms but slowing the progression, sadly these treatments do not work for
都不太理想 最终 我们带来这种问题
all MS sufferers. Ultimately, bringing like to this issue in an effort to
人们对研究的支持和资助是治愈MS的关键一步
support and fund research is an incredibly important step to erasing MS.
我们中的许多人都不理解与MS患者
And though many of us will never truly understand the challenges of
一起生活的难度
living with MS,
我们可以一起努力去唤起人们的意识 如果你可以
we can work together to raise awareness. We would be so grateful if you could
抽出一点时间 让你的家人朋友观看这个视频 一起解决MS的问题
take a moment and pass this video on to your family and friends and join in the
我们将会十分感激
effort to end MS.
这集的秒懂科普由 23andMe赞助播出 23andMe是一个
This episode of AsapSCIENCE is supported by 23andMe. 23andMe is a
DNA分析服务组织 它可以让你探索你自己的基因 让你知道
DNA analysis service that allows you to explore your own genes, whether you’re
你是否健康和患病的风险
interested in discovering a global origins for understand you’re health and your
你可以进入23andme.com的网址
risk for disease, be they sure to check out 23andme.com/asap
在他们的工具的帮助下 得知你现在的健康状态
With the help of their DNA kits, connect to your past, learn about your present health and
而且有可能在未来成为基因调查的一部分
potentially be a part of future genetic research all at 23andme.com/asap
订阅来观看更多的每周科学视频
And subscribe for more weekly science videos.

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