There’s a lot of misinformation out there
about what it means to be transgender
But recently, scientists have begun to look more closely
into the neurology, physiology, and psychology behind it.
So today, we’re gonna break down what Science does know
in a respectful and educational way.
嗨 我是Gigi Gorgeous
Hey guys! I’m Gigi Gorgeous
And today, I’ m here with AsapSCIENCE
to break down ‘The Science of Being Transgender’
Before we get too deep into it,
we have to look at your genetic sex
or the chromosomes you have.
These were determined right after fertilization
when the sperm cell from your father,
which carries an ‘X’ or a ‘Y’ chromosome
fuse with the egg from your mother,
which carries an ＇X＇chromosome.
But until 6 or 7 weeks after fertilization,
both ‘XY’ and ‘XX’ embryos have identical gonads.
Around 7 weeks the male sex organs start to develop
because of a gene on the ‘Y’ chromosome called ‘SRY’
It causes cells to become more specialized
and these cells creates ‘Testosterone’
which in turn trigger the development of the structure
like the penis and scrotum
while other cells block female development
by degenerating the female ducts.
However, in female development
because there is no ‘Y’ chromosome with the ‘SRY’ gene,
these ducts stay intact
and become the uterus, cervix, upper vagina, and the oviduct
分化为 子宫 子宫颈 上阴道 和输卵管
with the help of Estrogen, and chemical secreted by the early kidney.
But it’s not always that simple.
There are some kinds even rare combinations
比如 XXY XXX XXYY等类型
like ‘XXY’, ‘XXX’, ‘XXYY’ etc.
And even people with ‘XX’ chromosomes
that develop male genitals and characteristics
due to a piece of the Y chromosome breaking off
and switching places to an ‘X’ chromosome.
But sexual differentiation in a brain
actually happens much later than gonadal differentiation.
And yes, although controversial,
male and female brains have structural and functional
diffrences between each other.
Studies have found that males generally have
更大的大脑 小脑 和海马体
a larger cerebrum, cerebellum, and hippocampus.
While females have higher-density left frontal lobes,
and larger volumes in the right frontal lobe.
So what exactly do we see
when we look in the brain of a transgender person?
Several studies have shown
that transgender brain are both structurally and functionally
more similar to their experienced gender identity
than their biological sex.
One study found that transwomen
who despite being a scient male at birth
had a smaller female size structure in the hypothalamus.
MIR scans also show the brain structures of trans people
to be more similar in thickness to
their experienced gender and not their sex.
Finally the furanone and androstadienone causes
different hypothalami responses in male & female brains
And when individuals with ‘Gender Dysphoria’ were exposed to it,
hypothalamic response match their Perceived gender
rather than their sex.
These studies help to highlight
how masculinisations or feminisations of the Gonads
is not always the same as the brain
and that there’s a difference between
your sex or your anatomy and your gender
or how we perceive our own bodies.
There also seems to be a genetic component to transgender identity.
Looking at family histories,
gender identity in congruence seems to run in the family,
meaning they maybe inherited
The CYP17 gene which controls the body’s level
of sex hormones has a changed allele that
is expressed frequently in trans man.
Although more research could be done,
scientists are currently looking at over 3 Million DNA Markers for transgender identity
to investigate any genetic link for being trans.
Even though scientific studies validate the experience of transgender people
they’re still suffering from more depression and anxiety than the general public.
The risk of suicide is more prominent in transgender people
who have been rejected by their family
discriminated in the workplace, or in health care.
Sucide risks seems to decreased after gender transitioning,
suggesting that gender dysphoria can cause
an extreme amount of emotional pain
even to the point of suicide.
If you, a family member, or a friend
is suffering from gender dysphoria,
there are few links in the description for more information.
Thank you so much Gigi for being part of this video,
it means so much
and we’re happy you’re here to do this the best.
我想感谢你们 使用你们的频道 平台
I wanna thank you guys for using your channel, your platform
validating transgender experiences with science
which just brings us closer to equality.
If you guys wanna check out Gigi’s Channel,
we’ll put links in the description or in the screen somewhere.
Otherwise, you can subscribe for more Science here every week
and we’ll see you next time.