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银屑病的类型、症状、病因、病理和治疗方法 – 译学馆
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银屑病的类型、症状、病因、病理和治疗方法

Psoriasis: Types, Symptoms, Causes, Pathology, and Treatment, Animation

银屑病是一种非常常见的皮肤炎症
Psoriasis is a very common inflammatory skin condition
全球约有3%的人口患有此病
affecting about 3% of the world population.
这是一种伴随着阶段性的部分或完全缓解期的
It is a chronic disease that evolves
以炎症突然性复发的形式
in the form of recurrent inflammatory flare-ups
不断恶化的慢性疾病
followed by periods of partial or complete remission.
银屑病可以发病于任何一个年龄段 但以青壮年期为主
Psoriasis can begin at any age but often develops in young adulthood.
这种疾病看起来具有传染性 其实并没有
The disease may look contagious, but it is not.
最常见的一种叫做斑块型银屑病
The most common type, known as plaque psoriasis,
表现的症状为产生红肿的
is characterized by the presence of red, raised,
发痒的鳞状皮肤
itchy and scaly patches of skin.
红斑通常会出现在头皮处
The plaques usually appear on the scalp,
膝盖上及手肘后
in front of the knees and behind the elbows.
不常见的类型包括:滴状银屑病:
Less common types include:- Guttate psoriasis:
皮肤上产生无数的大面积覆盖的小斑点
lesions occur in the form of small numerous spots over a large area of the body.
这种类型主要发生于儿童和年轻人
This type primarily affects children and young adults.
-皮褶银屑病:
– Inverse psoriasis:
在发炎的皮肤上会出现光滑斑块 摩擦和汗液可能导致病情加重
smooth patches of inflamed skin that worsen with friction and sweating.
这通常发生在皮肤皱褶处
These are usually found in between skin folds.
脓疱型银屑病:是一种不常见病症 病征为出现无传染性的脓包
– Pustular psoriasis: an uncommon form withpus-filled, non-infectious blisters.
红皮病型银屑病:最不常见却很严重
– Erythrodermic: a rare but severe,
随着病变蔓延到全身 会有伤及性命的危险
potentially life-threatening form, with wide spread lesions all over the body
银屑病具有很强的遗传倾向
Psoriasis has a strong genetic component,
因为许多基因与银屑病的易感性相关
with multiple genes linked to the susceptibility to the disease.
这些基因中的大多数与免疫系统有关
Most of the identified genes are involved in the immune system,
尤其是炎症路径
notably inflammatory pathways.
一些家庭中 银屑病是一种常染色体显性遗传特征
In some families, psoriasis is an autosomal dominant trait.
疾病的突发可能由很多因素引起
Flare-ups can be trigged by a variety of factors,
这些因素包括感染 外伤 压力
including infections, traumatic injuries, stress,
吸烟 酗酒和某种药物
smoking, alcohol use and certain medications.
第一次发病通常于上呼吸道感染之后出现
The firet lesion usually appears after anupper respiratory tract infection.
确切的机制还不完全明确
The exact mechanism is not fully understood
但是倾向于与一种身体炎症的过度反应有关
but likely to involve an overreaction of the body’s inflamatory responds.
炎症会导致血管舒张 释放化学因子 引起发红和发痒
Inflammation dilates blood vessels, releasingchemicals, resulting in redness and itchiness.
大量被活化的T细胞浸润表皮
Large numbers of activated T-cells infiltrate the epidermis
诱发皮肤细胞的增殖
and induce proliferation of skin cells.
这些细胞分化和移行非常迅速
The cells divide and move up quickly,
增殖时间无需数周 只要几天
in the matter of days instead of weeks.
这使得细胞在皮肤表层迅速聚积
This causes cells to build up rapidly on the surface of the skin
从而形成鳞状斑块病损
and form scaly patches.
常见的并发症包括眼部疾病 就是眼部银屑病
Common complications include eye diseases, known as ocular psoriasis;
还有发生于手指和脚趾的慢性关节炎 也就是银屑病关节炎
and chronic joint inflammation in the fingers and toes, known as psoriatic arthritis.
同时银屑病会增加心血管病 肥胖 糖尿病
Psoriasis also associates with higher risksof cardiovascular diseases, obesity, diabetes,
自卑感和失落感的患病风险
low self-esteem and depression.
大多数患有轻微或中度银屑病的患者可以通过使用外用药剂得到有效治疗
Most people with mild to moderate psoriasis can be treated effectively with topical agents.
这些药膏和软膏有抗炎
These creams and ointments have several effects: anti-inflammatory,
减缓皮肤细胞增殖
slowing down skin cell growth,
以及缓解掉皮和瘙痒的功效
and reducing scaling and itching.
重度银屑病人可以通过额外的治疗缓解病情 比如说光线疗法
Severe psoriasis may benefit from additional treatment such as phototherapy –
自然或人造紫外线可以减慢皮肤细胞增生以及减轻炎症
The use of natural or artificial UV light to slow skin cell proliferation and reduce inflammation.
紫外线治疗的时长应该受到控制 以免造成不必要的皮肤损伤和癌症
The exposure time should be controlled to avoid unwanted skin damage and cancers.
当其他方法疗效不佳时 应考虑采用系统疗法
Systematic treatment is considered when othermethods fail.
这种疗法包括服用口服药
This type of treatment involves oral administration
或者注射可减缓细胞生长
or injection of drugs that reduce cell growth
或者抑制免疫系统的药物
or suppress the immune system.

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本视频对银屑病进行了简单的介绍,有利于增进人们对此病的了解。

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https://www.youtube.com/watch?v=MbmizU2O1XY

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