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打一针可以提供你所有需要的疫苗 – 译学馆
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打一针可以提供你所有需要的疫苗

One Shot Could Provide All the Vaccines You'll Ever Need

所有婴儿有一个共同点
There is one thing all babies have in common,
他们的免疫系统比成年人要差
They are born with weaker immune system than adults.
我们知道这冰冷的世界有很多可怕的疾病
We know there are some terrible diseases out here in the cold, cold world, and we also
我们也知道如果训练免疫系统识别这些威胁
know that if you train the immune system to recognize those threats
它会进行抵抗
they’ll fight them off!
问题是 父母们不放心疫苗
The problem is, vaccinations make parents uncomfortable.
他们不放心你给他们的小公主 大胖小子
There’s this thing, and you’re stabbing it into my tiny princess or bouncing baby
或者小宝贝打的针
boy or princess boy or whatever!
为了更好的提高免疫力 父母不得按照防疫表打疫苗
In order to train the immune system in the best way possible, parents have to follow
通常会找医生
a strict schedule of injections… often returning to the doctor.
总是这样
All The time.
看看这个防疫表!
Look at this schedule!
每个月都有不同的疫苗 特定的时间也有特定的疫苗要打
Different things every month, and ranges and specific vaccines at specific times.This is
这么多时间限制
so much scheduling.
国家不同 时间表也不一样
And different countries have different schedules because they’re exposed to different diseases
因为不同时间接触的疾病不一样
at different times.
如果两年内你又有了个小孩
What if you have another kid in 2 years?
那么你不得不平衡两个小孩的时间
Then you have to balance two of these schedules
再加上你照顾小孩的时间和自己的生活
plus your regular parenting and non-parenting lives.
要是我说研究员已经找到打一针解决所有问题的方法
What if I told you that researchers had figured out how to do this all of this stuff in one..
只打一针
Literally one shot.
你明白的
you know.
这是凯文.麦克休我是马赛诸塞洲理工学院的
This is Kevin McHugh I’m a postdoctoral fellow at the Massachusetts
博士后
Institute of Technology
他和他的团队研究出解决办法
He’s worked with a team to engineer a solution.
微构小型”咖啡杯”或者立方体
Micro-fabricated tiny ‘coffee cups’ or cubes
一旦进入体内就会逐渐分解
that slowly degrade once inside the body.
你只要一次性隐性注入所有需要的疫苗
You can just go one time, and deliver all your vaccines potentially in that one visit,
一系列的传染病就无法威胁到你
then you can have someone fully protected against an array of infectious diseases.
这个疫苗的组成和普通的一样 但他含有一种特殊的聚合物
This vaccine has the same contents as a regular vaccine but it contains a special polymer
叫做聚乳酸-羟基乙酸共聚物或者是PLGA
called (poly(lactic-co-glycolic acid) or PLGA.
很多被FDA认可的装置都包含有它
It’s in a lot of different FDA approved devices so we think it can be translated to the clinic
所以我们认为它会比新型材料更容易应用于临床
more readily than perhaps a new material”
小咖啡杯的制作过程和电脑芯片有点类似
The little coffee cups are made using a process similar to the one for computer chips, but
但它用到是PLGA 而不是硅
instead of silicon they use PLGA.
咖啡杯事实上有顶部和底部
The coffee cup analogy works, we actually have a bottom, we have a top, and we fill
我们往中间灌满液体
the liquid in the middle.
微粒足够小 能够流过针头
The particles are small enough to flow through a needle
所以医生只要把它注入到肌肉里
so a doctor just needs to inject it into the muscle.
接下来的几个月 体内的水和聚合物缓慢发生反应
Over the next few months, water in the body slowly reacts with the copolymer in a process
这个过程叫水解作用
called hydrolysis.
它会分解成很多小分子乙醇酸和乳酸 肾脏分解乙醇酸
It breaks down into tiny bits of glycolic acid, cleared by the kidneys, and lactic acid
而乳酸则分解成CO2和水 这是自然现象
which breaks down into CO2 and water, it’s natural!
如果你感觉像被灼烧 那就是乳酸
When you feel the burn, that’s lactic acid!
所以说 不用经常去医院打疫苗或者担心
So again, instead of dozens of visits and injections and worry… one injection, and
只要一针就完事
done.
科学引领潮流!
Science take the wheel!
凯文的论文显示PLGA的分解是可预知的
Kevin’s paper shows that the PLGA breaks down in a predictable way, so they can plan
所以可以根据需要设计疫苗及其它成分
the vaccinations and boosters depending on what needs to happen.
微粒对免疫系统而言非常大 不需要担心
The particles are too big for the immune system to worry about
但也很小 不会影响病患
but too small to bother the patient.
目前为止 我们仍然对接种疫苗有顾虑
Even still, we can’t talk vaccinations without worries.
一份2015年的报道发现93%的内科医生曾被父母拒绝过
A 2015 report found 93% of physicians were told by some parents ‘No Way.
不行 一次性这么多针对我的宝宝而言太多了
That’s too many shots at once for my baby.’
我们还是根据自己的安排打疫苗
Let’s go by our own schedule.
即使这样 将近90%医生觉得不按防疫表
Even though almost 90-percent of doctors felt by deviating from this schedule, they’d
进行注射是让孩子(或者社区)冒险 一些医生还是没有按照规定注射
put the kid (or community) at risk… some doctors deviated anyway because parents were
是因为父母担心纠结
worried or upset.
CDC提到 一些父母(毫无理由地)认为
The CDC mentions some parents (with no evidence or training mind you) felt all these vaccinations
这些疫苗可能会压垮孩子的免疫系统 而理论上并不会
might overwhelm their kid’s immune system… which science says — it will not.
一次接种疫苗就够了 父母也少一些担心
Having one vaccination that does the whole job, could relieve a lot of worried parents,
我们不会给你孩子打很多针 只打一针
we don’t have to poke your baby a lot, just one time!
这个新兴科技不仅给大多中产阶级父母带来方便
This future tech isn’t just convenient for overbooked middle-class parents either, a
在发展中国家 一次疫苗接种能够改变命运
single vaccination is life changing in the developing world.
每年数以百万计的婴儿得不到疫苗
There’s a lot millions of infants every single year that either don’t get any vaccines or
或者打过一次疫苗 但没有把剩下的全部打完
get one vaccine but don’t get the full complement of injections along the way on a schedule
所以这些婴儿还是面临着被各种传染疾病感染的风险
and so all these infants out there are at risk for you know contracting these different infectious diseases
这肯定不是资金问题 而是渠道问题
and … it’s not necessarily, you know, a cost issue, it’s a delivery issue — how do
怎么把疫苗送到人们手里
you get the vaccines to the people.
给孩子一次性便利疫苗简直可以
Having a single, time-release vaccination for children could quite literally change
改变世界
the world.
帮助上百万有或没有医保的人提高免疫力
Helping millions of people with and without healthcare security develop immune-strength,
活得更健康长寿
and live longer, healthier lives.
希望你喜欢这个视频
I hope you liked this video!
走之前 可以用一秒的时间订个阅吗
Before you go, can y’all take a quick sec and subscribe?
可以帮我们把节目做得更好
It really helps us make the show better!
谢谢
Thanks.
如果你觉得这种疫苗很奇怪 人类的第一针疫苗岂不是更奇怪
If you think this vaccine is weird, the very first vaccine was way weirder.
它跟牛 小孩和奇怪的科学有关
It had to do with cows, and kids and weird science.
可以查一查
Check it out here.
你有发现什么新奇好玩的科技 我们应该报道的吗?
Have you found any other cool new technology we should cover?
推特上告诉我 @TraceDominguez 或者在评论上留言
Tweet me @TraceDominguez, or tell us in the comments.
谢谢观看Seeker
And thanks for watching Seeker.

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视频概述

新研究成果,只需要一次注射疫苗,不用再频繁去注射。

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视频来源

https://www.youtube.com/watch?v=qQ1VKYX4Vl0

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