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东京大学: 纳米医药的研究与发展 – 译学馆
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东京大学: 纳米医药的研究与发展

Meet Horacio Cabral — Developing lifesaving nanomedicine

My name is Horacio Cabral.
我是Horacio Cabral
I’m an associate professor at the department of Bio-engineering at the University of Tokyo
东京大学生物工程系的副教授
I’m from Argentina and I’ve been working here for more than 15 years
我来自阿根廷 到这工作已经超过15年了
I’ve been working in the field of nano-medicine
我的研究领域是纳米医药
which is the study of nano-scale materials
即对纳米级材料的研究
We aim to develop new types of nano-medicines
我们致力于开发新型的纳米医药
for the treatment of intractable diseases
来治疗棘手的疾病
To prepare our nano medicines we develop new types of polymer
为制备出纳米医药 我们开发了新型聚合物
and these polymers are synthesized in a very controlled manner…
这些聚合物的合成方式极其可控
so that we can get high quality materials
这样我们就能得到高质量材料
that will be used to self-assemble
而它将用于自组装
Once we construct our nano-medicines
一旦我们构建出纳米医药
and we characterize them, we study the stability of the nano-medicines in different conditions
我们就能研究其特性 在不同环境下的稳定性
We also study the activity of the nano-medicines
我们也研究纳米医药的活性
for example to kill cancer cells
比如说 其杀灭癌细胞
or to reduce specific proteins in the disease cells
或者减少疾病细胞特定蛋白的活性
One unique characteristic of our nano-medicine is
这种纳米医药的一个独特性质是
that we can control the size.
我们可以控制它的大小
This size control is quite advantageous for treating pancreatic cancer.
控制大小对于治疗胰腺癌很有用
because pancreatic cancer has a very dense collagen network
因为胰腺癌有致密的胶原蛋白网
which prevents the penetration of drugs
能阻碍药物穿透
We can develop nano-medicines that are small enough
我们将纳米医药变得足够小
to penetrate into the pancreatic tumor
能够穿透进胰腺肿瘤
and achieve very effective treatments against the disease
就能有效治疗此疾病
Some of these formulations have actually translated into human clinical trials
其中有些制剂已进入人体临床试验阶段
and are being studied in Japan and also overseas
这些研究正在日本及海外其他国家进行
Currently there are 15 students in my lab,
现在我的实验室有15个学生
half of them is foreigners, half of them is from Japan
一半来自海外 一半来自日本
and they belong to different research areas
他们分属于不同的研究领域
including materials engineering, chemical engineering, pharmacy, medical school
包括材料工程系 化学工程系 药学系 医学系
So each one provides a unique viewpoint
所以 每个学生都能提供独特的视角
to the nano medicine problem
来观察纳米医药问题
For many years
多年来
we have been focused on developing nano-medicines for cancer treatment
我们专注于开发治疗癌症的纳米医药
And now we are starting to explore
现在我们也开始探索
treatment of brain diseases, such as Alzheimer’s disease or diabetes,
阿尔兹海默症等脑部疾病或是糖尿病的治疗方法
which are a major struggle for many patients around the world
这些病症极大地困扰着全世界许多病人
So by designing new type of treatments
因此 制造出新型医药
we will benefit humanity in the near future
会在不久的将来为人类带来福音

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视频概述

东京大学这个副教授以及他的学生们正在研究能使更多的疾病得到治疗的纳米医药,他们希望在不久的将来,得病的人能够用纳米医药得到更好的治疗。

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视频来源

https://www.youtube.com/watch?v=U506y6smD4o

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