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你可以健康活多久? – 译学馆
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你可以健康活多久?

How Long Can You Be Healthy?

本视频由Elysium Health友情赞助
This video was sponsored by Elysium Health
生产膳食补充剂Basis
which produces a dieter supplement named Basis.
临床证明能增加人体NAD+水平
That’s clinically proven to increase NAD+ levels in the body,
与Ms. BeautyPhile联合出品
and in collaboration with Ms. BeautyPhile.
这是简·考玛22岁时的照片
This is a picture of Jeanne Calment
拍摄于1897年
at the age of 22 in 1897.
她出生于1876年
She was born in 1876,
也就是大小角战役发生的那一年
the same here as the Battle of the Little Bighorn that saw
见证了美军被美洲西部原部落击败
the US Army defeated by Native American tribes on the western frontier.
第二年 她见证了武士起义
The next year of her life saw samurai revolt
反抗日本政府
against the Japanese government.
当她39岁时
And by the time she was 39,
斐迪南大公遭到刺杀 引发了一战
Archduke Franz Ferdinand had been assassinated sparking the first world war.
到她114岁时
By the time she was 114,
见证了柏林墙的倒塌
she witnessed the collapse of the Berlin Wall.
当她1997年去世时
And by the time of her death in 1997
她已经122岁 成为了世界上
at the age of 122 years she achieved the longest lifespan
最长寿的人
of a human ever recorded.
每个人都梦想着
Everybody has dreamt at some point
长生不老 甚至永生
of living a long life or even an infinite life.
在上个世纪 科学家帮助了我们
And science has helped with us through the last century
通过研发疫苗和抗生素
with inventions like vaccines and antibiotics.
极大得提高了全世界
These have helped to dramatically raise humanity’s life expectancy
人类的寿命
at birth across the world,
以美国为例 1900年到2010年间
like in the United States where between 1900 and 2010 life expectancy
人均寿命从47.3岁提高到78.7岁
increased from just 47.3 years up to 78.7 years.
但是在最近 寿命的提升的步伐减慢了
But further improvements in life expectancy have been slowing lately
很难找到治疗疑难杂症的药物
as medicine has struggled to find cures for more complicated diseases.
由于过量吸毒 酗酒 自杀和鸦片类危机
Because of overdoses, alcoholism, suicide and the opioid crisis,
在2016年 人类寿命自1993年起
2016 was the first year since 1993 that saw a decline
首次下降
in the American life expectancy.
尽管从全球范围来看
Even still life expectancy in the long run
人均寿命还是在增长
is still increasing around the world
但我们究竟能活多久 还不得而知
and it’s unknown currently how far the limit can be pushed.
研究如何提升寿命的科学家们
Scientists in search of increasing human lifespan
开始研究其他寿命极长的生物
point to other organisms with dramatically longer lifespans than our own.
像一些巨龟的寿命将近200岁
Like some giant tortoises that can reach near 200 years
还有一些小的水生物 比如水螅
and some small freshwater animals of the genus Hydra
几乎可以称得上是永生
that appear not to age at all.
阿尔伯特·爱因斯坦医学院的研究表明
One study from the Albert Einstein College of Medicine suggested that
人类能够达到的最大寿命是125岁
125 years is the maximum age limit that a human could ever reach.
然而其他科学家 像奥布里·德格雷
While other scientists like Aubrey de Grey believe the limit
认为人类寿命可以达到1000岁
could be pushed much further up to even 1,000 years.
所有这些声明都遭到一定的怀疑
All of these claims have been met with a fair amount of skepticism,
所以没人真正知道
so it seems that nobody really knows
人类寿命最长能达到多少岁
just how far human lifespan can be pushed,because of this uncertainty
正因为这样 最近对于科学家更重要的是
what’s become much more important lately to many scientists instead
一个人健康的寿命
is focusing on an individual’s health span.
你生命中健康的一段时间
The part of your life where you’re healthy,
数据表明 现在大部分人
there is data that suggests that most people alive now
对现在的预期寿命表示满足
would be content with having the current expected lifespan
前提是要健康
but with an improved health span.
因为年纪越大 慢性病越常见
Because chronic diseases become more common the older you get,
仅仅提升寿命的长度的话
increasing a person’s lifespan alone
并不能提高生存质量
likely won’t do much to increase their quality of life.
相反 提高一个人的健康水平
Instead, improving an individual’s health span
将给生活带来大量好处
will add much more value to their life.
现在市面上已经有几种不同的产品
There are already several different products on the market right now
对应不同的生物路径 科学家研究
targeting different biological pathways that scientists are researching to determine
是否能提高健康水平
if they can support health span.
然而 需要注意
It’s important to understand however
这些都是新的研究
that all of this is new research
这些产品也不能代替其中的一个产品
and that these products are not interchangeable with that being said,
也就是我们说的二甲双胍
one of these products is metformin,
经FDA认证 治疗2型糖尿病的药物
an FDA approved drug that treats type 2 diabetes.
当在小鼠和蛔虫身上做试验时
When used in trials on mice and roundworms,
这个药物能提高它们的健康水平和寿命
the drug improved both their health spans and lifespans,
而且已经在进行人体试验
and it’s currently undergoing human trials.
但是其他提高健康水平的方法就不依赖医学
But other ways supporting healthspan may not require medication at all though.
这里有三个有趣的研究
There are three interesting areas of research to highlight here.
第一个最近的研究表明
First, a recent study found that when mice
让小鼠定时进食
were allowed to eat only at certain times during the day,
它们的新陈代谢更健康
their metabolisms became healthier,
当这个快速食谱放在人身上
when this fasting diet was applied to humans who only consumed
试验对象每月定时摄入700到1100卡路里
between 700 to 1100 calories for a period of time each month,
以降低血压和IGF-1的水平
in lowered blood pressure and reduced the hormone IGF-1,
它们与衰老和疾病有关
which is linked to both aging and disease.
也有用CRISPR-Cas9技术的基因编辑
There’s also the technology behind genome editing with CRISPR-Cas9,
本质上能把好的基因补上
which is essentially capable of turning good genes on
剔除坏的基因
and bad ones off,
如果你的基因像学校的论文作业
If your genes are like a school essay assignment then CRISPR-Cas9
CRISPR-Cas9则像改作业的
is like the spell check that can edit and correct them.
这项技术能特异性的指向衰老有关基因
This technology could specifically target genes that are associated with aging.
最后 另一个方法和热点话题是
Finally another method and hot topic for research is
通过提高NAD+水平来延长生命
by improving NAD+ levels later in your life.
NAD+是一种辅酶 存在于每个细胞
NAD+ is a coenzyme inside every cell of your body,
科学家认为是最重要的一种因素
which scientists believe is one of the most important factors
对于DNA的健康 能量的产生
for DNA health, energy creation,
新陈代谢节奏 还有数百个重要功能
circadian rhytm regulation and hundreds of other vital functions.
它们存在于每个存活的细胞
They can be found in every living cell,
但当你变老
but as you get older
你的NAD+水平开始下降 越来越少
your levels naturally begin to decline further and further.
现在有很多预临床和人体试验开始计划
There are many preclinical and human trials being planned right now
对于NAD+路径
for the NAD+ pathway,
但是为了提高未来的健康水平
but in order to try improving health span in the future
需要很多附加试验
will need trials for additional methods as well.
我们不知道寿命能有多长
We don’t know how the limits are right now,
但我认为这是好的
but I think that’s a cause for optimism,
因为问题的答案只被想象限制
because the answer might only be limited by our imagination.
每个人都应该尽可能健康
Everybody deserves to live as healthy a life as possible,
如果你想要更深层次的了解科学
so if you’re interested in learning more about the in-depth science
想提高你的NAD+水平
going on behind raising your NAD+ levels,
可以访问我们的网站
you can do so by visiting elysiumhealth.com
来试试经过临床实验的膳食补充品
and try their dietary supplement basis based on human clinical trials.
按建议剂量服用Basis的人们
People that took the recommended dose of Basis
看见他们的NAD水平增长了40%
saw their nad levels increase by 40 %.
Basis作为一种计划长期使用的补充品
Basis as a supplement designed for long-term use
是第三方测试纯度的
is third-party tested for purity
这基于超过25年的研究成果
and is based on over 25 years worth of research.
NAD+对于你的细胞健康是必需的
NAD+ is essential to the health of your cells
Basis会帮助增加你体内NAD+水平
and basis will help increase NAD+ levels in your body
点击下方的链接
by clicking the link in the description below,
你可以订购装有一个月的药片一瓶
you can order a single bottle with a month supply of pills
或者按月交货
or schedule routine monthly deliveries
我非常地感谢赞助这个视频的Elysium
I’m incredibly grateful to have had Elysium sponsor this video,
研究有基础的产品和科学是完美的匹配
there are perfect match of a hard science and research based product
在这个频道和视频上
to have on this channel and video.
如果你愿意支持RealLifeLore
So if you’d like to support RealLifeLore
并且想了解更多
and are curious to learn more
我再次强烈鼓励你点击链接
I once again strongly encourage you to click the link
在我们的网站上了解更多
in the description to learn more at ElysiumHealth.com.
别忘了看这个视频的下一部分
And please don’t forget to check out the next part of this video
在这里查看我的朋友Beauty女士的
by going over and checking out my friend Ms Beauty files channel
频道和视频
And her video here.

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视频来源

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