This video was sponsored by Elysium Health
which produces a dieter supplement named Basis.
That’s clinically proven to increase NAD+ levels in the body,
and in collaboration with Ms. BeautyPhile.
This is a picture of Jeanne Calment
at the age of 22 in 1897.
She was born in 1876,
the same here as the Battle of the Little Bighorn that saw
the US Army defeated by Native American tribes on the western frontier.
The next year of her life saw samurai revolt
against the Japanese government.
And by the time she was 39,
Archduke Franz Ferdinand had been assassinated sparking the first world war.
By the time she was 114,
she witnessed the collapse of the Berlin Wall.
And by the time of her death in 1997
at the age of 122 years she achieved the longest lifespan
of a human ever recorded.
Everybody has dreamt at some point
of living a long life or even an infinite life.
And science has helped with us through the last century
with inventions like vaccines and antibiotics.
These have helped to dramatically raise humanity’s life expectancy
at birth across the world,
like in the United States where between 1900 and 2010 life expectancy
increased from just 47.3 years up to 78.7 years.
But further improvements in life expectancy have been slowing lately
as medicine has struggled to find cures for more complicated diseases.
由于过量吸毒 酗酒 自杀和鸦片类危机
Because of overdoses, alcoholism, suicide and the opioid crisis,
2016 was the first year since 1993 that saw a decline
in the American life expectancy.
Even still life expectancy in the long run
is still increasing around the world
and it’s unknown currently how far the limit can be pushed.
Scientists in search of increasing human lifespan
point to other organisms with dramatically longer lifespans than our own.
Like some giant tortoises that can reach near 200 years
and some small freshwater animals of the genus Hydra
that appear not to age at all.
One study from the Albert Einstein College of Medicine suggested that
125 years is the maximum age limit that a human could ever reach.
While other scientists like Aubrey de Grey believe the limit
could be pushed much further up to even 1,000 years.
All of these claims have been met with a fair amount of skepticism,
so it seems that nobody really knows
just how far human lifespan can be pushed,because of this uncertainty
what’s become much more important lately to many scientists instead
is focusing on an individual’s health span.
The part of your life where you’re healthy,
there is data that suggests that most people alive now
would be content with having the current expected lifespan
but with an improved health span.
Because chronic diseases become more common the older you get,
increasing a person’s lifespan alone
likely won’t do much to increase their quality of life.
Instead, improving an individual’s health span
will add much more value to their life.
There are already several different products on the market right now
targeting different biological pathways that scientists are researching to determine
if they can support health span.
It’s important to understand however
that all of this is new research
and that these products are not interchangeable with that being said,
one of these products is metformin,
an FDA approved drug that treats type 2 diabetes.
When used in trials on mice and roundworms,
the drug improved both their health spans and lifespans,
and it’s currently undergoing human trials.
But other ways supporting healthspan may not require medication at all though.
There are three interesting areas of research to highlight here.
First, a recent study found that when mice
were allowed to eat only at certain times during the day,
their metabolisms became healthier,
when this fasting diet was applied to humans who only consumed
between 700 to 1100 calories for a period of time each month,
in lowered blood pressure and reduced the hormone IGF-1,
which is linked to both aging and disease.
There’s also the technology behind genome editing with CRISPR-Cas9,
which is essentially capable of turning good genes on
and bad ones off,
If your genes are like a school essay assignment then CRISPR-Cas9
is like the spell check that can edit and correct them.
This technology could specifically target genes that are associated with aging.
Finally another method and hot topic for research is
by improving NAD+ levels later in your life.
NAD+ is a coenzyme inside every cell of your body,
which scientists believe is one of the most important factors
for DNA health, energy creation,
circadian rhytm regulation and hundreds of other vital functions.
They can be found in every living cell,
but as you get older
your levels naturally begin to decline further and further.
There are many preclinical and human trials being planned right now
for the NAD+ pathway,
but in order to try improving health span in the future
will need trials for additional methods as well.
We don’t know how the limits are right now,
but I think that’s a cause for optimism,
because the answer might only be limited by our imagination.
Everybody deserves to live as healthy a life as possible,
so if you’re interested in learning more about the in-depth science
going on behind raising your NAD+ levels,
you can do so by visiting elysiumhealth.com
and try their dietary supplement basis based on human clinical trials.
People that took the recommended dose of Basis
saw their nad levels increase by 40 %.
Basis as a supplement designed for long-term use
is third-party tested for purity
and is based on over 25 years worth of research.
NAD+ is essential to the health of your cells
and basis will help increase NAD+ levels in your body
by clicking the link in the description below,
you can order a single bottle with a month supply of pills
or schedule routine monthly deliveries
I’m incredibly grateful to have had Elysium sponsor this video,
there are perfect match of a hard science and research based product
to have on this channel and video.
So if you’d like to support RealLifeLore
and are curious to learn more
I once again strongly encourage you to click the link
in the description to learn more at ElysiumHealth.com.
And please don’t forget to check out the next part of this video
by going over and checking out my friend Ms Beauty files channel
And her video here.